Home/Blog/12 Best Supplements for Healthy Aging & Longevity

12 Best Supplements for Healthy Aging & Longevity

By Rachel Link, RD, MS

February 22, 2024

It may feel like every week you hear about a new supplement that you “should” be taking. But if you're interested in the best supplements for healthy aging and longevity, how do you differentiate between the best supplements that are actually worthy investments versus those that are mostly a waste? 

Truth be told, for most people some vitamins, minerals, probiotics and other nutrients are more valuable than others, based on both their broad benefits and the likelihood that you may be lacking them in your diet. For example, experts say that the most common nutrient shortfalls in women include vitamins like B12, D, minerals like iron and calcium, and even nutrients like omega-3s.

Including the best supplements described below in your daily routine can help take care of your entire body — your gut, joints, skin, muscles, bones, brain and more — and set you up for healthy longevity.

Let’s break down which top supplements qualify as being most important for the majority of people as they age, and touch upon their key benefits and uses.

1. Collagen

Collagen is a type of structural protein that’s found throughout the body, particularly in connective tissues. As we age, our collagen production begins to naturally slow down, which can increase normal signs of aging.

Collagen supplements are used to generally support healthy skin (such as skin elasticity and improving the appearance of crow's feet), hair and nails, joint function and gut health. Using a collagen powder supplement each day is a convenient and effective way to help give the body the building blocks, in the form of amino acids, that it needs to make its own collagen, which supports healthy tissues and has benefits such as promoting gut lining integrity, skin elasticity and joint health.

How to use:

Collagen powder is usually unflavored and can be mixed into coffee, smoothies, oatmeal, baked goods, soups, and many other recipes. Aim to consume between 1–3 servings daily, or about 10 to 30 grams of collagen protein. As always, you should read and follow all label directions as well as consult your healthcare professional prior to starting any new dietary or lifestyle regimen, including supplementation.

Ancient Nutrition’s Multi Collagen Protein powder features 10 types of collagen from four real food sources, plus it contains no fillers, sugar, artificial flavors or artificial preservatives, ensuring you get the highest quality collagen available. It features hydrolyzed collagen, meaning the protein molecules are broken into smaller molecules, making them easier for your body to digest, absorb and use.

You can choose from a variety of Multi Collagen Protein flavors based on your preferences — including Chocolate, Vanilla, Cucumber Lime and Strawberry Lemonade — and from several formulas designed specifically to support healthy sleep, skin health and joint health, such as Multi Collagen Protein Beauty Within and Multi Collagen Capsules - Joint + Mobility. There are also Multi Collagen Capsules.

Meanwhile, Multi Collagen Advanced is the new collagen line with supplements that also help one lose weight and fat, gain muscle and strength, and even rapidly hydrate and promote healthy detoxification.

Shop the Multi Collagen Advanced line here.

2. Bone Broth Protein

Bone Broth Protein powder naturally features collagen, which as you know supports healthy connective tissues throughout the body (including tendons, ligaments, bones and more), as well as a healthy gut function and healthy skin.

Additionally, Bone Broth Protein is chock full of minerals and nutrients — including glucosamine, chondroitin sulfate, hyaluronic acid, calcium, magnesium, potassium and phosphorus — that further support healthy muscles, bones and more. Moreover, it provides 20 grams of protein per serving, and many folks don't get enough protein in their diet as they age.

When made into a powdered supplement, Bone Broth Protein is derived from real bone broth liquid but dehydrated. This concentrated powder is shelf-stable, convenient and has many uses in a variety of recipes. It’s an excellent way to obtain more amino acids, especially the types called glycine, proline, hydroxyproline and arginine, that are not found in high amounts in meat, fish and eggs.

How to use:

Ancient Nutrition’s Bone Broth Protein powders provide many of the same benefits as homemade bone broth, but are much more versatile and easier to consume on a regular basis, since they require no preparation or cooking.

Bone Broth Protein can be consumed 1–3 times daily to increase protein/amino acid intake. (Be sure to read and follow label directions for use.) Bone Broth Protein powders come in several flavors and mix easily with water, green juice, coffee, almond/coconut milk or smoothies, and can even be baked with or cooked.

Vegan or vegetarian? Then consider plant protein powders, such as Ancient Nutrition’s Plant Protein+ which is made with a blend of multiple super seeds such as flax and hemp.

This one-of-a-kind protein powder is made without animal products, dairy, grains and soy, making it suitable for those following a wide range of diet plans and who want the best supplements for healthy aging.

3. Probiotics

Probiotics are live microorganisms, including bacteria, yeast and other microbes, that live inside the gut and form the microbiome, which is actually where the majority of the immune system is located. Having higher levels of certain probiotic strains in the gut is associated with a range of health benefits, including support for immune function, nutrient absorption, elimination and digestive health.

Adding probiotic supplements to your daily routine can help to keep your digestion on track by maintaining normal gut transit time and reducing occasional constipation, gas and bloating. Some types of probiotic formulas can also support a healthy inflammation response, another key aspect of immune health, while others feature specific strains that are tailored for women or men.

To get the most benefits from probiotics, you want to consume a supplement that contains “hardy” and survivable microbial strains, which is what you’ll find in Ancient Nutrition’s soil based organism (SBO) probiotics.

The goal is to supplement with beneficial microbes such as SBOs that actually make their way to the right parts of the gut, without being partially killed off by stomach acid and heat. Additionally, SBO probiotics don’t require refrigeration since they can survive at room temperature.

How to use:

SBO Probiotics are best absorbed when taken on an empty stomach about 30 minutes before a meal. However you can take them with a meal if this easier for you to remember; consistency is what’s more important.

If you’re looking for a quality probiotic supplement, consider one of Ancient Nutrition’s SBO Probiotic formulas, which feature between 25 and 100 CFUs* (*at time of manufacture) of SBOs per serving in combination with organic fermented blends of superfoods for extra mind-body support. These unique formulas also feature prebiotics and postbiotics to create a “trifecta effect” that supports absorption. Prebiotics provide the fuel necessary for probiotics to grow and thrive, while postbiotics help to maintain a balance of gut flora.

A general recommendation for Ancient Nutrition’s SBO Probiotics is for adults to take two capsules daily with 8 ounces of water. 

Also consider Regenerative Organic Certified® Probiotics, which is the first-ever combination of prebiotics, postbiotics and 30 diverse probiotics strains, plus Regenerative Organic Certified® superfoods to support gut health. For example, Regenerative Organic Certified™ Once Daily Probiotics with one capsule per day.

4. Multivitamin

Taking a high-quality multivitamin every day is a smart way to meet your nutritional needs and fill in potential gaps in your diet. For example, did you know it's estimated that up to 70 percent (or more) of American adults don’t get enough vitamin D or magnesium from their diets alone?

A multivitamin is a well-rounded way to help fill in any key nutrient gaps in the diet, helping to support higher energy levels, bone health, eye and skin health, and much more.

Ancient Nutrition offers several unique multivitamin formulas tailored to the specific vitamin needs of women and men, including: Ancient Multi Women’s, which features 100 percent or more of the daily value of 14 essential vitamins and minerals plus multi-kingdom ingredients inspired by Traditional Chinese Method, and Ancient Multi Men’s which includes functional mushrooms and herbs for extra immune system and cardiovascular support, and beyond.

How to use:

Each product is somewhat different — such as Ancient Multivitamin Women's 40+ and Ancient Multivitamin Men's 40+ alongside Once Dailies — so always read serving and usage recommendations carefully. Most often you’ll need to take 1–3 capsules daily, usually with a meal to support absorption.

5. Omega-3s

Omega-3 fatty acids are the same beneficial fats found in heart-healthy fishes like salmon and sardines. They play a key role in cardiovascular health, brain function, healthy growth and development, a healthy inflammatory response and more.

However, because most people eating a “modern diet” don’t tend to consume fatty fish very often, plus many include a lot of processed foods in their diet made with refined vegetable oils, which means most (up to 90 percent of Americans) are falling short of their omega-3 needs.

Ancient Omegas (see below) is an omega-3 supplement that makes it easy to get a balanced serving of different essential fatty acids, including omegas 3s, 6s and 9s. When consumed in a healthy ratio, these fats contribute to healthy aging, joint health and offer whole body support.

How to use:

How much omega-3 per day? Most adults can benefit from about 1,000 milligrams of omega-3 fatty acids daily. A general recommendation of Ancient Nutrition’s Omega supplements is three capsules daily with 8 ounces of water or juice for most adults.

Ancient Omegas Whole Body features a special combination of organic plant and wild ocean omega fatty acids, including from chia oil and wild-caught tuna and New Zealand hoki. It supplies you with certain unique omegas you may have never heard of, like eicosatetraenoic acid (ETA), plus ancient botanicals like lemon peel oil and black pepper fruit oil to support absorption.

6. Vitamin D

Vitamin D is an essential nutrient that’s found in very few food sources. It’s been nicknamed the “sunshine vitamin” because our skin is actually able to synthesize vitamin D when exposed to sunlight.

However, unfortunately many adults and children are also thought to be lacking in this key nutrient, resulting in low vitamin D levels, because most people avoid spending too much time in direct sunlight these days.

Taking a vitamin D supplement is recommended for most adults, babies and children because this is an easy and effective way to help meet your vitamin D requirement. Maintaining normal levels is important for strengthening bones and boosting calcium absorption, as well as supporting healthy immune function, a positive outlook and healthy weight management.

How to use:

Vitamin D2 and D3 are the two most common forms of vitamin D. D3 is thought to be generally more effective at increasing vitamin D levels in the body compared to vitamin D2, since it’s the more “active” and bioavailable form. 

The recommended dietary allowance (RDA) for vitamin D varies based on age. Children and adults under 70 years need at least 600 IUs per day. Oftentimes, vitamin D supplement doses can exceed the RDA, and many recommend using a vitamin D supplement with 5,000 IU or more to ensure adequate blood levels.

Ancient Nutrition’s Vitamin D supplement contains 5,000 IU of probiotic-fermented vitamin D3 per serving. Additionally, it features multi-kingdom ingredients inspired by TCM (Traditional Chinese Method), such as bone broth and liver powder, along with 95 mcg of vitamin K for further immune, cardiovascular and bone health support.

Vitamin D is a fat-soluble vitamin, so if your supplement doesn’t contain an oil, you should take your vitamin D with a meal that contains a source of fat to optimize absorption.

7. Vitamin B12

While you can obtain vitamin B12 from foods like meat and fish, you may not be acquiring enough if your diet isn’t rich in these sources, or absorbing it adequately for a variety of reasons. Vitamin B12 is water-soluble, meaning it needs to be replenished often for you to maintain normal levels via consumption of B12 foods and/or B12 supplements.

Other than nutritional yeast, most plant foods don’t provide B12, which is why it’s generally recommended that those following a vegan/vegetarian diet supplement with this vitamin.

Getting enough B12 is important for supporting healthy energy levels, maintaining healthy red blood cells, and supporting cognitive and neurological health. Other benefits include promoting restful sleep, eye health, exercise recovery, a healthy pregnancy, and offering cardiovascular health support.

How to use:

Ancient Nutrition's B12 supplement is a co-enzymated form of methylcobalamin taken in capsule form that is formulated from real food sources, which can help to support absorption. This unique formula also features multi-kingdom ingredients inspired by TCM (Traditional Chinese Method) — including antioxidants and reishi mushroom extract that generally helps support a healthy immune system.

The daily recommended intake (the minimum amount that people need for general health) for B12 is 2.4 mcg per day for adults, 2.6 mcg per day during pregnancy and 2.8 mcg per day while breastfeeding; however, you should always read and follow the label directions and suggested use. If supplementing to help meet your needs, B12 can be taken with or without food.

8. Vitamin C

Vitamin C, also known as ascorbic acid in supplement form, is an essential vitamin that we must get from our diets. It’s “essential” because the human body doesn’t make any of its own vitamin C.

A daily vitamin C supplement is an easy way to increase levels of this vitamin in your body in order to support a healthy you. In general, older adults in particular may want to supplement with vitamin C because it helps to form blood vessels, cartilage, muscle and collagen in bones.

Vitamin C supplements and foods can help to support a healthy immune system, and are also supportive of healthy vision and skin health.

How to use:

It’s recommended that adult men get at least 90 milligrams of vitamin C per day, and that adult women get at least 75 milligrams daily. These are considered minimum amounts to meet most adults’ needs; therefore, more may be helpful in some instances.

For Ancient Nutrition's Vitamin C supplement with 900 milligrams of Vitamin C, simply take 2 capsules with 8 ounces of water or your favorite beverage. 

9. Vitamin E

A fat-soluble vitamin with many important processes in the body, this bioavailable, natural vitamin E also functions as an antioxidant. Ancient Nutrition'svitamin E supplementis powered by enzyme-activation and features a potent combination of hair-, skin- and bone-supporting real-food ingredients.

Vitamin E is found naturally in foods such as raw or sprouted nuts and seeds, leafy green vegetables, eggs and butter.

How to use:

Ancient Nutrition carefully sourced a potent and natural form of vitamin E for this supplement. Ancient Nutrients Vitamin E is made without any binders, fillers, artificial colors, sweeteners or additives.

With 95 milligrams of natural vitamin E, take 2 capsules per day with 8 ounces of water or your favorite beverage.

10. Vitamin K

Vitamin K is important for building and maintaining strong bones, for normal blood clotting, and for supporting heart health. This vitamin plays a role in normal bone metabolism and helps to generally ensure that calcium gets to the right places in the body, such as the bones and teeth.

Many women, for instance, fall short in this valuable nutrient, which is a shame considering it plays a major role in facilitating healthy cardiovascular functions and supporting arterial health.

There are two main types of vitamin K, both of which we acquire from our diets. Vitamin K1 is found in vegetables, while vitamin K2 is found in things like dairy products.

Additionally, supplementing with vitamin K2 can help to support strong bones and other functions if your diet tends to supply low amounts.

How to use:

Ancient Nutrition's vitamin K2 supplement includes 90 micrograms of soy-free, fermented vitamin K2. With or without food, take 1 capsule per day with 8 ounces of water or your favorite beverage.

11. Turmeric

Turmeric has been used in cooking and natural health for centuries, solidifying its well-deserved status as a superfood ingredient. Not only has it been shown to support a healthy response to inflammation, recent research has unearthed several other potential benefits of turmeric tablets or capsules for joints, skin and other areas of the body.

The best turmeric supplements should also contain piperine, which is a compound found in black pepper that enhances curcumin absorption. While more studies need to be conducted, one animal study indicated that the administration of piperine may increase curcumin absorption by up to 2,000 percent. This explains why this warming spice is often combined with turmeric in traditional Ayurvedic practices.

The best turmeric supplements are also made with fermented turmeric root, like Ancient Nutrition's Organic Turmeric Tablets (see below). Why? Fermentation supports the body’s ability to absorb the herb’s compounds.

How to use:

Although the ideal turmeric dosage may vary based on many different factors, some research typically suggests that you should get at least one gram of curcumin per day to promote better health. 

Ancient Nutrition's Organic Turmeric Tablets is made with organic turmeric root extract and fermented turmeric root. Take 1 tablet per day with 8 ounces of water or your favorite beverage.

12. Super Greens Powders

Do you eat enough greens? The herbs, greens and botanicals added to these powders are nutrient-filled sources of essential vitamins and minerals. This means that these supplements may help fill in gaps in your diet, especially if you don’t regularly eat vegetables and fruits.

Benefits of adding a supergreens powder to your diet can include increased antioxidant intake, help with healthy detoxification, support healthy digestive function, help with maintaining healthy gut microflora and support for general gut health, and promoting proper elimination.

How to use:

Ancient Nutrition’s Organic SuperGreens Powder (Greens Flavor) is one of the most convenient ways you can increase your daily greens intake.

A general recommendation is for adults to consume one scoop daily mixed with 8 ounces of water, or your favorite hot or cold beverage.

Try our powdered greens in a power-packed green smoothie or protein shake, or simply added to fresh squeezed juice. Having a serving in the morning is a great way to give yourself a natural energy boost. Just add a scoop to a glass of cold water, mix well and sip.

If you're interested in other flavors, or tablet or gummy versions, check out the Organic SuperGreens page.